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Table 2 Diagnostic accuracy of LAMP and microscopy

From: Determination of the prevalence of African trypanosome species in indigenous dogs of Mambwe district, eastern Zambia, by loop-mediated isothermal amplification

 

Microscopy

 
 

CAT present

CAT absent

Total

LAMP-positive

True positive (TP) = 14

False positive (FP) = 6

TP + FP = 20

LAMP-negative

False negative (FN) = 0

True negative(TN) = 217

TN + FN = 217

Total

TP + FN = 14

TN + FP = 223

237

  1. Note:
  2. LAMP Sensitivity = TP / (TP + FN) = 100%.
  3. LAMP Specificity = TN / (TN + FP) = 97.3%.
  4. LAMP Positive predictive value (PPV) = TP / (TP + FP) = 70%.
  5. LAMP Negative predictive value (NPV) = TN / (TN + FN) = 100%.
  6. LAMP Positive likelihood ratio (LR+) = sensitivity / (1 – specificity) = 37.
  7. LAMP Negative likelihood ratio (LR-) = (1 – sensitivity) / specificity = 0.