Figure 3
From: Bovine besnoitiosis emerging in Central-Eastern Europe, Hungary
Histopathological changes during besnoitiosis: (A) numerous tissue cysts in the dermis and epithelial desquamation; (B) cyst showing three-layered wall: outermost connective tissue, middle layer containing host cell nuclei and the internal parasitophorous vacuole membrane surrounding the bradyzoites; (C) infiltration with histiocytes and eosinophilic granulocytes around cysts; and (D) occlusion of sebaceous gland duct.