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Table 2 LTR genetic variability on transcriptional and regulatory sites in HIV-1 subtype C chronically infected individuals with and without helminths coinfections

From: Triple NF-kB binding sites and LTR sequence similarities in HIV-1C isolates irrespective of helminth co-infection

Variables

Mutation frequency (x10−2)a

 

Enhancer region

Promotor region

TAR element

 

NF-κBI

NF-κBII

NF-κBIII

SPI

SP II

SP III

E-box I

TATA box

E-box II

TAR

With helminths infection

8.5

12.4

2.6

12.4

0

8.8

2.5

3.1

1.7

7.1

Without helminths infection

9.3

11.3

1.6

14.1

0

5.3

5.0

2.7

1.7

7.7

  1. aPolymorphic changes are calculated by dividing the number of changes with respect to ETH2220 sequence by total number of nucleotides sequenced in each region; NF-κB-Nuclear factor Kappa B; TAR element-Transcription trans-activator.