Figure 1From: An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3Cell-cycle analysis of indirubin-treated cells by flow cytometry. DNA content of parasites treated with vehicle only (A, control, DMSO < 0.1%) and parasites treated with GI50 concentration of compounds 11 (D), 17 (E). Compounds 6BIO (B) and 5-Me-6-BIO (C) were used as controls. The DNA content was measured by staining cells with propidium iodide (PI) and the cell-cycle status was analyzed by flow cytometry.Back to article page