Skip to main content

Advertisement

Table 2 Effects of ivermectin on various parasite stages

From: Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections

Parameters Definition
Microfilaricidal effect The increase in microfilarial mortality.
Anti-fertility effect The temporary reduction in the production of live microfilariae by adult female worms (also known as embryostatic effect).
Anti-macrofilarial effect The long-term, cumulative adverse effect on adult worms due to prolonged exposure of the parasites to the drug (represented in the model as a per dose reduction in the per capita rate of microfilarial production by adult female worms).