Table 2 Effects of ivermectin on various parasite stages
Parameters | Definition |
|---|---|
Microfilaricidal effect | The increase in microfilarial mortality. |
Anti-fertility effect | The temporary reduction in the production of live microfilariae by adult female worms (also known as embryostatic effect). |
Anti-macrofilarial effect | The long-term, cumulative adverse effect on adult worms due to prolonged exposure of the parasites to the drug (represented in the model as a per dose reduction in the per capita rate of microfilarial production by adult female worms). |