Skip to main content

Advertisement

Table 4 Baseline (pre-control) model-derived burden of disease (DALYs) associated with onchocerciasis in savannah areas of Africa at different levels of endemicity

From: Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections

  Disability Adjusted Life Years (DALYs)§(per 1000 person-years)
Years of life with disability (YLD) Years of life lost (YLL)  
Pre-control endemicity‡ Blindness (ratio)* Visual impairment (ratio)* Troublesome itch (ratio)* Associated with vision loss (ratio)* Associated with high microfilarial load (ratio)* Total DALY burden (ratio)*
Mesoendemic 3.6 1.4 7.0 2.7 5.9 20.6
Hyperendemic 11.4 (3.2) 4.4 (3.1) 15.3 (2.2) 8.8 (3.3) 29.6 (5.0) 69.5 (3.4)
Highly hyperendemic 49.0 (13.6) 18.8 (13.4) 21.0 (3.0) 37.0 (13.7) 72.3 (12.3) 198.7 (9.6)
  1. §See Additional file1: Text S2 for a detailed description of the methods used to calculate DALYs.
  2. In line with WHO guidelines, a discount rate of 3% was applied to YLLs[56].
  3. *Ratio of metric with respect to the value for the mesoendemic level.
  4. ‡ Pre-control microfilarial prevalence as in Table 1.