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Table 3 Flea larvae emergence from eggs of parent fleas fed on blood containing fluralaner at sub-insecticidal concentrations

From: Fluralaner, a novel isoxazoline, prevents flea (Ctenocephalides felis) reproduction in vitro and in a simulated home environment

Fluralaner (ng/mL) Larval emergence
Exposure daya
  3 4 5 8 9 10
50.0 NA NA NA NA NA NA
25.0 NA NA NA NA NA NA
12.5 no NA NA yes yes NA
6.25 yes yes yes yes yes yes
3.13 yes yes yes yes yes yes
1.56 yes yes yes yes yes yes
0.78 yes yes yes yes yes yes
0.39 yes yes yes yes yes yes
0.19 yes yes yes yes yes yes
0.09 yes yes yes yes yes yes
  1. aNo assessment of larval emergence was performed on exposure days 6 and 7.
  2. NA: not applicable because fleas were either killed or did not lay eggs (Table 1 and Table 2).