Table 1 Characteristics of study population
Characteristic | N’Dakonankro | Yoho | Bozi | P value |
|---|---|---|---|---|
February 2010 | ||||
No. of subjects | 301 | 290 | 306 | |
No. of males:females (%) | 151:150 (50:50) | 150:140 (52:48) | 146:160 (48:52) | 0.613 |
Mean age in years (standard deviation) | 6.7 (2.3) | 7.6 (2.6) | 8.7 (5.7) | <0.001† |
No. of children who slept under an ITN or LLIN the night before the interview (%, 95% CI) | 75 (24.9, 20.1-30.2) | 44 (15.2, 11.2-19.8) | 66 (21.6, 17.1-26.6) | 0.012† |
No. of febrile cases (%, 95% CI) | 145 (48.2, 42.4-54.0) | 123 (42.4, 36.7-48.3) | 104 (34.0, 28.7-39.6) | 0.002† |
No. of slide positive (%, 95% CI) | 167 (55.5, 49.7-61.2) | 187 (64.5, 58.7-70.0) | 140 (45.8, 40.1-51.6) | <0.001† |
No. of RDT positive (%, 95% CI) | 186 (61.8, 56.0-67.3) | 190 (65.5, 59.7-71.0) | 174 (56.9, 51.1-62.5) | 0.093 |
Geometric mean of parasitaemia, expressed in parasites/μl of blood (95% CI) | 37.5 (26.0-54.1) | 79.9 (54.7-116.6) | 18.5 (12.8-26.7) | |
Sensitivity; specificity; PPV; NPV (%, 95% CI) | 79.6 (75.7-83.0); 61.0 (56.1-65.8); 71.5 (67.5-75.2); 70.9 (65.8-75.6) | |||
November 2011 | ||||
No. of subjects | 45 | 56 | 68 | |
No. of males:females (%) | 25:20 (56:44) | 42:14 (75:25) | 35:33 (52:48) | 0.021† |
Mean age in years (standard deviation) | 9.3 (1.7) | 9.4 (1.8) | 10.3 (3.2) | 0.010 |
No. of children who slept under an ITN or LLIN the night before the interview (%, 95% CI) | 21 (46.7, 31.7-62.1) | 28 (50.0, 36.3-63.7) | 21 (30.9, 20.2-43.3) | 0.070 |
No. of febrile cases (%, 95% CI) | 2 (4.4, 0.5-15.1) | 6 (10.7, 4.0-21.9) | 4 (5.9, 1.6-14.4) | 0.485 |
No. of slide positive (%, 95% CI) | 35 (77.8, 63.0-88.8) | 40 (71.4, 57.8-82.7) | 59 (86.8, 76.4-93.8) | 0.156 |
No. of RDT positive (%, 95% CI) | 29 (64.4, 48.8-78.1) | 38 (67.9, 54.0-79.8) | 47 (69.1, 56.8-79.8) | 0.909 |
Geometric mean of parasitaemia, expressed in parasites/μl of blood (95% CI) | 118.9 (50.1-282.2) | 78.9 (35.9-173.4) | 136.0 (77.3-239.0) | |
Sensitivity; specificity; PPV; NPV (%, 95% CI) | 80.6 (72.9-86.9); 83.3 (67.2-93.6); 94.7 (88.9-98.0); 53.6 (39.7-67.0) | |||
May 2012 | ||||
No. of subjects | 137 | 153 | 126 | |
No. of males:females (%) | 71:66 (52:48) | 77:76 (50:50) | 73:53 (58:42) | 0.418 |
Mean age in years (standard deviation) | 10.7 (0.9) | 11.3 (2.0) | 12.2 (2.5) | <0.001† |
No. of children who slept under an ITN or LLIN the night before the interview (%, 95% CI) | 63 (46.0, 37.4-54.7) | 50 (32.7, 25.3-40.7) | 55 (43.7, 34.8-52.8) | 0.047† |
No. of febrile cases (%, 95% CI) | 4 (2.9, 0.8-7.3) | 3 (2.0, 0.4-5.6) | 5 (4.0, 1.3-9.0) | 0.621 |
No. of slide positive (%, 95% CI) | 111 (81.0, 73.4-87.2) | 113 (73.9, 66.1-80.6) | 102 (81.6, 73.0-87.4) | 0.203 |
No. of RDT positive (%, 95% CI) | 96 (70.1, 61.7-77.6) | 108 (70.6, 62.7-77.7) | 79 (63.2, 53.6-71.1) | 0.356 |
Geometric mean of parasitaemia, expressed in parasites/μl of blood (95% CI) | 158.4 (104.1-241.1) | 68.7 (45.5-103.7) | 125.9 (81.3-194.8) | |
Sensitivity; specificity; PPV; NPV (%, 95% CI) | 76.1 (71.1-80.6); 60.7 (49.7-70.9); 87.6 (83.2-91.2); 40.9 (32.4-49.8) | |||