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Figure 7 | Parasites & Vectors

Figure 7

From: The pathogenesis of optic neuritis caused by Angiostrongylus cantonensis in BALB/c mice

Figure 7

Histopathological alteration of the optic nerve in the A. cantonensis -infected mice after TBD treatment. A1-G1: HE staining, bar = 100 μm; A2-F2: electronic photo, bar = 0.5 μm. (A1-A2): Normal optic nerve of mice (B1-B2): Optic nerve in untreated mice infected with A. cantonensis for 14 d; (C1-C2): Optic nerve in mice treated with TBD for 3 d, after 14 d of A. cantonensis infection; (D1-D2): Optic nerve in untreated mice infected with A. cantonensis s for 21 d; (E1-E2): optic nerve in mice treated with TBD for 7 d after 14 d of A. cantonensis infection; (F1-F2): Optic nerve in untreated mice infected with A. cantonensis for 28 d; (G1-G2): Optic nerve in mice treated with TBD for 14 d after 14 d A. cantonensis infection. (H): Data are mean ± SEM of axon numbers with or without TBD treatment for 3 d, 7 d, and 14 d, respectively. (I) Data are mean ± SEM for the demyelination rate with or without TBD treatment for 3 d, 7 d, and 14 d, respectively. *Statistically significant when compared with control (0 d infection) (P < 0.05).

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