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Figure 1 | Parasites & Vectors

Figure 1

From: Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis

Figure 1

Toxoplasma encephalitis model was established. Microscopic observation of the brain tissues of mice latently infected with cyst-forming T. gondii Wh6 strain (genotype Chinese 1) reactivated by cyclophosphamide administration. (A①) and (A③), a single cyst (arrows) in the cortex of chronically infected mice; (A②) necrosis and inflammatory infiltration noted in foci of recrudescence; (A④) free tachyzoites in TE (×400). The sections were incubated with mouse anti-Toxoplasma SAG1 monoclonal antibody and peroxidase-antiperoxidase-coupled secondary antibody, followed by DAB colorization. Figure B, hemiplegia and paraplegia in model mice with Toxoplasma encephalitis.

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