Figure 4

Determination of the availability of the predicted epitope. The molecular surface of the homology model of β-CA from Ancylostoma caninum is shown as solid grey and the target epitope sequence was excluded from the surface presentation. The epitope residues exposed to solvent are shown as red VdW spheres and numbered, while buried residues are shown with green spheres. An alignment containing PDB 1EKJ and the corresponding sequence from Ancylostoma caninum predicted β-CA is shown. The numbering of the residues in the alignment is according to the Ancylostoma caninum sequence. The yellow residues in the alignment indicate partially buried structure.