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Table 4 Results and performance of the five diagnostic assays for cutaneous leishmaniasis

From: Molecular diagnosis of cutaneous leishmaniasis and identification of the causative Leishmania species in Morocco by using three PCR-based assays

Diagnostic method Number of positives True positives Number of negatives True negatives Sensitivity (%) Specificity (%) PPV (%) NPV (%) χ ± [SE]
Direct examination 19 19 39 14 43 100 100 36 0.270 ± 0.110
Culture 13 13 45 14 29 100 100 31 0.170 ± 0.102
13A/13B PCR 48 44 10 10 100 71 92 100 0.791 ± 0.101
Lmj4/Uni21 PCR 35 35 23 14 79 100 100 61 0.652 ± 0.106
ITS1-PCR 45 44 13 13 100 93 98 100 0.950 ± 0.040
PCR c 44 44 14 14 100 100 100 100  
Total   44   14      
  1. PPV: Positive Predictive Value; NPV: Negative Predictive Value; PCRc: PCR consensus results.
  2. 95% CI for sensitivity, specificity, PPV and NPV.