Table 1 IC 50 values for ferroquine (FQ), hydroxyl-ferroquine (FQ-OH), ruthenoquine (RQ), chloroquine (CQ) and mefloquine (MQ) in non-cancerous MRC-5 and HeLa cancer cells
From: In vitro and in vivo antischistosomal activity of ferroquine derivatives
Complex | IC50MRC-5 (µM) | IC50HeLa (µM) |
|---|---|---|
Cisplatin | 7.9 ± 1.2 | 11.5 ± 2.9 |
FQ | 24.4 ± 0.9 | 10.1 ± 0.3 |
FQ-OH | 22.6 ± 1.2 | 16.8 ± 1.5 |
RQ | 21.9 ± 2.6 | 8.8 ± 0.41 |
CQ | 55.1 ± 1.3 | 87.0 ± 1.5 |
MQ | 16.7 ± 0.2 | 6.7 ± 0.7 |