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Figure 3 | Parasites & Vectors

Figure 3

From: Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection

Figure 3

LaSP-EX induces Th1 systemic polarization. Mice were vaccinated and infected as described for Figure 2. At day 7 of infection, their spleen cells were re-stimulated in vitro with LaAg (5 μg/mL), and after 48 hours of culture the levels of IFN-γ (A), IL-4 (B), IL-10 (C) and TGF-β (D) were measured in the supernatants. The data displayed is representative of three independent experiments. Means ± SD (n = 5). *p ≤ 0.05 in relation to PBS.

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