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Figure 2 | Parasites & Vectors

Figure 2

From: LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4+ and CD8+) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis

Figure 2

Cellular profile of circulating lymphocytes in dogs submitted to different vaccination protocols before and after challenge with L. infantum plus SGE. C (control;); Sal (SGE;); LBSal (killed L. braziliensis vaccine plus SGE;); LBSapSal (killed L. braziliensis vaccine plus saponin plus SGE;): the x-axis displays the times at which the assays were conducted (Tbc: time before challenge with L. infantum; and 20, 90, 274, 435, 541, and 885 days after challenge [dac] with L. infantum), and the y-axis represents the mean values of (A) CD5+, (B) CD4+, (C) CD8+ cells, and (D) CD4+/CD8+ ratio, the white and black bars represented the control and LBSapSal groups, respectively. Significant differences (p < 0.05) between the LBSapSal group and the C, Sal, and LBSal groups are indicated, respectively, by the letters a, b, and c. *Significant difference (p < 0.05) between the LBSapSal group and the control C group in CD4+/CD8+ ratio.

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