Figure 2From: LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4+ and CD8+) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpisCellular profile of circulating lymphocytes in dogs submitted to different vaccination protocols before and after challenge with L. infantum plus SGE. C (control;); Sal (SGE;); LBSal (killed L. braziliensis vaccine plus SGE;); LBSapSal (killed L. braziliensis vaccine plus saponin plus SGE;): the x-axis displays the times at which the assays were conducted (Tbc: time before challenge with L. infantum; and 20, 90, 274, 435, 541, and 885 days after challenge [dac] with L. infantum), and the y-axis represents the mean values of (A) CD5+, (B) CD4+, (C) CD8+ cells, and (D) CD4+/CD8+ ratio, the white and black bars represented the control and LBSapSal groups, respectively. Significant differences (p < 0.05) between the LBSapSal group and the C, Sal, and LBSal groups are indicated, respectively, by the letters a, b, and c. *Significant difference (p < 0.05) between the LBSapSal group and the control C group in CD4+/CD8+ ratio.Back to article page