| |
Bravecto™ (fluralaner)
|
Frontline™ (fipronil)
|
p value
|
Lower 97.5% 1-sided C.I.a
|
|---|
|
Fleas
| | | | |
|
Week 2
|
89.57%
|
62.30%
|
<0.0001
|
0.1498
|
|
Week 4
|
94.87%
|
63.93%
|
<0.0001
|
0.1916
|
|
Week 8
|
95.65%
|
70.49%
|
<0.0001
|
0.1416
|
|
Week 12
|
97.39%
|
81.97%
|
<0.0001
|
0.0586
|
|
Ticks
| | | | |
|
Week 2
|
97.67%
|
89.47%
|
0.0006
|
-0.0575
|
|
Week 4
|
97.67%
|
84.21%
|
0.0001
|
-0.0175
|
|
Week 8
|
97.67%
|
94.74%
|
0.0024
|
-0.0953
|
|
Week 12
|
100.0%
|
100.0%
|
n/ab
|
n/ab
|
- aResult greater than -0.15 required to declare significant non-inferiority. Result greater than 0 required to declare significant one-sided superiority with α = 0.025.
- bNo statistical test as all households were free of ticks at week 12.
- n/a: not applicable.
