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Table 2 Fluralaner pharmacokinetic parameters following oral administration (25 mg/kg) to fasted or fed dogs

From: The effect of food on the pharmacokinetics of oral fluralaner in dogs

Parameter Unit Fasted group Fed group P value Ratio (fed/fasted)
   Mean ± SD Mean ± SD   
(range) (range)
Cmax (ng/mL) 1591 ± 708 3377 ± 669 0.0015 2.1
(1037–2683) (2325 – 4326)
tmax (day) 1.3 ± 1.2 1.4 ± 1.3 0.8096 -
(0.17 – 3.00) (0.33 – 4.00)
AUC0-91d (day*ng/mL) 31369 ± 20654 78785 ± 11440 0.0022 2.5
(14316 – 63557) (60862 – 91854)
  1. SD: Standard deviation.