Table 6 Frequency distribution by group of dogs with abnormalities recorded following the first treatment
Time point | No. of animals with abnormalities recorded per group | Analysis | Conclusion | |||
|---|---|---|---|---|---|---|
Control group | 1X group | 3X group | 5X group | |||
Clinical assessment | 2 | 5 | 1 | 1 | Number of animals with abnormalities higher in 1X group than in controls, but similar to controls in 3X and 5X group; no dose–response relationship | Not treatment related |
Physical examination | 4 | 4 | 4 | 3 | Number of animals with abnormalities similar to controls; no dose–response relationship | Not treatment related |