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Figure 1 | Parasites & Vectors

Figure 1

From: A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

Figure 1

Comparative larvicidal activity of SAFDs against Brugia in WT versus SCID mice. Percentage recoveries of Bm L4 larvae from the peritoneal cavities of mice eight days after inoculation with 100 Bm L3 and commencement of a seven day oral regimen of 50 mg/kg qd albendazole (ABZ), diethylcarbamazine (DEC) or 15 mg/kg qd ivermectin (IVM). Circle plots are recoveries from BALB/c WT mice whilst square plots are derived from BALB/c SCID mice. Error bars are mean +/−SEM% recoveries per group. Data is pooled from two individual experiments for WT and one experiment for SCID mice (n = 4/group). Significant differences (1 way ANOVA with Bonferroni multiple comparison) are indicated P < 0.001***, P < 0.01**, P < 0.05*.

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