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Table 1 Parasitological observations of Onchocerca ochengi onchocercomata post-implantation into SCID mice

From: A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

Mouse strain/ID

Number/location

Vascularisation

Motile females*

Motile males*

Motile mf*

BALB/c SCID 1

4 ip

4/4

4/4

2/4

nd

BALB/c SCID 2

4 ip

2/4

4/4

0/4

nd

BALB/c SCID 3

4 ip

0/4

4/4

0/4

nd

BALB/c SCID 4

4 ip

0/4

4/4

2/4

nd

BALB/c SCID 5

4 ip

1/4

0/4

2/4

nd

BALB/c SCID 6

4 ip

2/4

4/4

2/4

nd

CB.17 SCID 1

4 sc

4/4

2/2

0/2

yes

CB.17 SCID 2

4 sc

4/4

3/3

1/3

yes

  1. Intraperitoneal implantation (ip), sub cutaneous implantation (sc).
  2. *motility assessed by dissection microscope +4 h after excision of nodule grafts, disruption of nodule capsule and culture in complete medium at 37°C/5%CO2.
  3. nd – not done.
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Parasites & Vectors

ISSN: 1756-3305

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