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Figure 5 | Parasites & Vectors

Figure 5

From: Antihistamine response: a dynamically refined function at the host-tick interface

Figure 5

Additional histamine does not explore the H1R active site in the presence of the double bound Ra-HBP2. The panels on the left depict the histamine trajectories according to its distance (Å) from the COM of the H1R (x-axis) and its respective histamine PELE binding energy. The panels on the right depict the histamine trajectories according to its distance from the COM of the tick Ra-HBP (x-axis) and the human H1R (y-axis). The circled cluster is within the trajectories of the third histamine binding site(s) represented in Figure 6.

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