Table 4 BM differential count and dysplastic changes in 83 dogs infected by different CVBD pathogens (*)
From: Evaluation of blood and bone marrow in selected canine vector-borne diseases
Bone marrow | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Differential count | Dysplasia | |||||||||||||
Ap | Hc | Li | Co-i | Tot | Ap | Hc | Li | Co-i | Tot | |||||
BM lineage | N/10 (%) | N/33 (%) | N/13 (%) | N/27 (%) | N/83 (%) | Precursors | Abnormalities | N/10 (%) | N/33 (%) | N/13 (%) | N/27 (%) | N/83 (%) | ||
Erythroid | Normal | 6 (60) | 20 (60.6) | 3 (23.0) | 14 (51.8) | 43 (51.8) | - | |||||||
Hyperplasia | 1 (10) | 9 (27.3) | 2 (15.4) | 7 (25.9) | 19 (22.9) | Promyelocytes | Bilobated nuclei | - | - | 1 (7.7) | 1 (3.7) | 2 (2.4) | ||
Hypoplasia | 3 (30) | 4 (12.1)A | 8 (61.5)Ab | 6 (22.2)b | 21 (25.3) | Metamyelocytes | Giants | 2 (20) | 10 (30.3) | 3 (23.0) | 6 (22.2) | 21 (25.3) | ||
EMI | Normal | 1 (10)c | 15 (45.4) | 2 (15.4) | 14 (51.8)c | 32 (38.5) | Basophilia cytoplasm | - | 4 (12.1) | 4 (30.8) | 4 (14.8) | 12 (14.4) | ||
Increased | 9 (90)D | 18 (54.5) | 9 (69.2) | 10 (37)D | 46 (55.4) | Vacuolized cytoplasm | - | - | 1 (7.7) | 1 (3.7) | 2 (2.4) | |||
Reduced | - | - | 2 (15.4) | 3 (11.1) | 5 (6) | Banda | Ring nuclei | - | 2 (6) | 1 (7.7) | - | 3 (3.6) | ||
Myeloid | Normal | 5 (50) | 20 (60.6) | 6 (46.1) | 14 (51.8) | 45 (54.2) | Basophilia cytoplasm | - | 1 (3.0) | - | - | 1 (1.2) | ||
Hyperplasia | 3 (30) | 2 (6) | 2 (15.4) | 3 (11.1) | 10 (12) | Segmented | Dohle bodies | 3 (30) | 6 (18.1) | 2 (15.4) | 4 (14.8) | 15 (18) | ||
Hypoplasia | 2 (20) | 11 (33.3) | 5 (38.4) | 10 (37) | 27 (32.5) | Hypersegmented | 6 (60) | 11 (33.3) | 7 (53.8) | 10 (37) | 34 (41) | |||
MMI | Normal | 2 (20) | 16 (48.5) | 8 (61.5) | 12 (44.4) | 38 (45.8) | Basophilia cytoplasm | 1 (10) | - | 1 (7.7) | - | 2 (2.4) | ||
Increased | 3 (30) | 6 (18.1) | 4 (30.8) | 8 (29.6) | 21 (25.3) | Monocytes/ Macrophages | Vacuolized cytoplasm | 3 (30)O | 0(0)Op | 1 (7.7) | 5 (18.5)p | 9 (10.8) | ||
Reduced | 5 (50) | 11 (33.3) | 1 (7.7) | 7 (25.9) | 24 (28.9) | Erythrophagocytosis | 2 (20) | 4 (12.1) | - | 5 (18.5) | 11 (13.2) | |||
Lymphocytic hyperplasia | 2 (20)e | 10 (30.3)F | 10 (76.9)eF | 15 (55.5) | 37 (44.6) | Platelet phagocytosis | 2 (20) | - | - | 1 (3.7) | 3 (3.6) | |||
Plasma cells hyperplasia | 2 (20)g | 15 (45.4) | 9 (69.2)g | 13 (48.1) | 39 (47) | Megakaryocytes | Dwarfs | 4 (40) | 8 (24.2) | 2 (15.4) | 4 (14.8) | 18 (21.7) | ||
Monocytic hyperplasia | 9 (90)h | 15 (45.4)h | 8 (61.5) | 17 (63) | 49 (59) | Hyperlobulated nuclei | 3 (30) | 4 (12.1) | 2 (15.4) | 2 (7.4) | 11 (13.2) | |||
Megakaryocytes | Normal | 2 (20) | 10 (30.3) | 4 (30.8) | 7 (25.9) | 23 (27.7) | Hypolobulated nuclei | - | 6 (18.1) | - | 1 (3.7) | 7 (8.4) | ||
Hyperplasia | 7 (70) | 22 (66.6) | 6 (46.1) | 14 (51.8) | 49 (59.0) | Disorganized nuclei | 7 (70)Qrs | 7 (21.2)Q | 3 (23.0)r | 6 (22.2)s | 23 (27.7) | |||
Hypoplasia | 1 (10) | 1 (3.0)i | 3 (23.0) | 6 (22.2)i | 11 (13.2) | Fragmented cytoplasm | 6 (60)TUv | 2 (6)T | 0(0)U | 4 (14.8)v | 12 (14.4) | |||
Mitosis | Normal | 6 (60)l | 17 (51.5)m | 2 (15.3)lm | 10 (37) | 35 (42.1) | Inclusions | 2 (20) | - | - | - | 2 (2.4) | ||
Increased | 3 (30) | 7 (21.2)n | 8 (61.5)n | 7 (25.9) | 25 (30.1) | Emperipolesis | 5 (50)z | 4 (12.1)zW | 2 (15.4) | 12 (44.4)W | 33 (39.8) | |||
Reduced | 1 (10) | 9 (27.3) | 3 (23.0) | 10 (37) | 23 (27.7) | Mitosis | Atypical | 0(0)X | 2 (6)Y | (61.5)XYβ | 3 (11.1) β | 10 (12) | ||