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Table 2 The BLAST results and GO analysis of positive hits from the yeast-two-hybrid screen

From: Identification of host proteins interacting with the integrin-like A domain of Toxoplasma gondii micronemal protein MIC2 by yeast-two-hybrid screening

Prey protein name

Genbank accession No.

Gene ontology classifications

Molecular function

Biological process

Late endosomal/lysosomal adaptor MAPK and mTOR activatr 1 (LAMTOR1)

NM_025605

Guanyl-nucleotide exchange factor activity

Cellular protein localization

Protein binding

Cellular response to amino acid stimulus

Protein complex scaffold

Endosome/Lysosome localization and organization

 

Positive regulation of MAPK cascade

 

Positive regulation of TOR signaling

 

Regulation of cholesterol homeostasis

 

Regulation of GTPase activity

 

Regulation of receptor recycling

Ribonuclease H2 subunit B (RNaseH2B)

NM_026001

RNA-DNA hybrid ribonuclease activity

In utero embryonic development

Negative regulation of gene expression

Positive regulation of fibroblast proliferation

Regulation of DNA damage checkpoint

Regulation of G2/M transition of mitotic cell cycle

Ribonucleotide metabolic process

RNA catabolic process