Anti-cE5 IgG1 and IgG4 responses. (A) Box plots of anti-cE5 IgG1 and IgG4 levels among the 207 individuals of the Aug 1994 survey. Boxes, whiskers, dots and P value as in Figure 1. IgG1 and IgG4 levels are expressed in ng/ml. (B) Scatter plot reporting the IgG1 (red) and IgG4 (black) antibody response to cE5 as function of age (n = 207). The best-fit lines (solid) and 95% CI (broken lines) are shown. Note that three data points are outside the axis limits.