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Figure 1 | Parasites & Vectors

Figure 1

From: The glycoprotein TRP36 of Ehrlichia sp. UFMG-EV and related cattle pathogen Ehrlichia sp. UFMT-BV evolved from a highly variable clade of E. canis under adaptive diversifying selection

Figure 1

Ehrlichia sp. UFMG-EV and Ehrlichia sp. UFMT-BV strain belong to a variable clade within E. canis . The trp36 (E. canis), gp47 (E. chaffeensis) and mucin like protein (E. ruminantium) nucleotides sequences were aligned and gap regions removed. Phylogenetic analyses were conducted using ML and NJ. The figure shows that Ehrlichia sp. UFMG-EV and Ehrlichia sp. UFMT-BV fall in a divergent clade of E. canis trp36 having low homology (less than 80%: red and pink boxes) compared to the isolate E. canis USA Jake 2. The amino acid sequence of the different TRP36 tandem repeats variants are shown (Coloured circles). The positions of the sequons are shown (red sticks on the boxes). The position of TRP36 ancestor clades I, II and III at internal branches (white circles) and position of sequons on ancestors (red sticks on white boxes) are also shown. The topologies obtained with the two methods were similar. The numbers above the internal branches represent bootstrap values. Only bootstrap values higher that 70 are shown.

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