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Table 1 Mean ± SD (g) and reduction (%) of the hydatid cysts weigh recovered from infected mice from the untreated control and treated groups MBZ-1% and MBZ-OS both dosed at 12.5 and 25 mg/kg daily during 14 days

From: An alternative mebendazole formulation for cystic echinococcosis: the treatment efficacy, pharmacokinetics and safety in mice

Groups

Dose (mg/kg per day × 14 days)

No. of mice

Mean cyst weight g (SD)

Reduction of cyst weight (%)

Untreated control

−

17

0.92 (1.22)

 

MBZ-1% tragacanth

25

16

0.47(0.69)

48.9

12.5

16

0.90 (1.15)

2.2

MBZ-OS

25

10

0.09 (0.07)*

90.2

12.5

12

0.16 (0.13)*

82.6

  1. *P < 0.05 vs. untreated control.