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Table 3 Histopathological changes in the livers of the mice from the uninfected control, untreated control and treated groups MBZ-1% tragacanth and MBZ-OS (10 mice per group) were observed by microscopy ( n = 5)

From: An alternative mebendazole formulation for cystic echinococcosis: the treatment efficacy, pharmacokinetics and safety in mice

Histopathologcial Changes

Uninfected control group

Untreated control group

MBZ-1% tragacanth

MBZ-OS

Congestion

0.0 (0.0)

0.0 (0.0)

0.0 (0.0)

0.0 (0.0)

Fatty infiltration

0.4 (0.3)

0.8 (0.5)*

0.6 (0.6)

0.6 (0.6)

Hepatocyte swelling

0.0 (0.0)

0.0 (0.0)

0.5 (0.7)

0.4 (0.6)

Inflammatory cell infiltration

0.0 (0.0)

0.0 (0.0)

0.0 (0.0)

0.0 (0.0)

  1. *P < 0.05 vs. uninfected group.