Skip to main content
Figure 1 | Parasites & Vectors

Figure 1

From: The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India

Figure 1

Comparison of Rhodamine and Calcein accumulation with retention in L. donovani clinical isolates. (A) Rhodamine accumulation in promastigotes of sensitive (2001) and resistant (39, 41, R-5) isolates under normal condition after 45 minutes of incubation. (B) Rhodamine accumulation in promastigotes of sensitive (2001) and resistant (39, 41, R-5) isolates under ATP depletion after 15 minutes of incubation. (C) Calcein accumulation in promastigotes of sensitive (2001) and resistant (39, 41, R-5) isolates under normal condition after 60 minutes of incubation. (D) Calcein accumulation in promastigotes of sensitive (2001) and resistant (39, 41, R-5) isolates under ATP depletion after 30 minutes of incubation. (E) Calcein retention in promastigotes of sensitive (2001) and resistant (39, 41, R-5) isolates without probenecid. (F) Calcein retention in promastigotes of sensitive (2001) and resistant (39, 41, R-5) isolates with probenecid. Data shown are results from 1 experiment and representative of 3 independent experiments.

Back to article page

Parasites & Vectors

ISSN: 1756-3305

Contact us