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Table 3 Times increase of total thiol levels in promastigotes of SAG resistant isolates 39, 41, R-5, with respect to the SAG sensitive isolate 2001 as calculated by the ratio of fluorescence of resistant isolates to sensitive isolate

From: The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India

Isolates

Normal condition

Energy depleted condition

39

0.6

1.17

41

1.5

2.07

R-5

0.05

0.26

  1. Data shown are results from 1 experiment and representative of 3 independent experiments.