Figure 2

Phylogenetic tree of Nudix hydrolase from 22 organisms using the Maximum parsimony method and plotted with MEGA. The GenBank accession number of each Nudix hydrolase is: T. spiralis (ABY60748.1), C. elegans (O45830.1), Haemonchus contortus (CDJ97233.1), Necator americanus (ETN70016.1), Ascaris suum (ADY47382.1), Brugia malayi (EDP34320.1), Trichinella pseudospiralis (ABL09502.1), Echinococcus granulosus (CDJ23656.1), Clonorchis sinensis (GAA49418.1), Crassostrea gigas (EKC30073.1), Anopheles darlingi (ETN61723.1), Homo sapiens (CAD01139.1), Schistosoma japonicum (AAW26860), Pediculus humanus corporis (EEB16642.1), Schistosoma mansoni (CCD60247.1), Hymenolepis microstoma (CDJ09496), Wuchereria bancrofti (EJW73682), Caenorhabditis brenneri (EGT47426), Drosophila melanogaster (CAI10730.1), Capitella teleta (ELT97831), Amphimedon queenslandica (XP_003389450), Strongylocentrotus purpuratus (XP_003729509.1), Pediculus humanus corporis (EEB16642.1). Bootstrap values which are higher than 90 are indicated on branches. The tree was rooted using Homo sapiens.