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Figure 5 | Parasites & Vectors

Figure 5

From: Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression

Figure 5

Aca-lpp-1 encodes a lipid phosphate phosphatase. A. Aca-LPP-1b translated amino acid sequence aligned with its C. elegans ortholog T28D9.3b1. Identical residues are in red, and conserved residues in blue. The phosphatase active site domains are highlighted in yellow, and the conserved residues required for activity are marked with an asterisk. The transmembrane domains are highlighted in green, and the conserved N-linked glycosylation site is marked by a dollar sign. B. Structure of LPP-1 showing transmembrane domains. Active site residues are found on extracellular loops 2 and 3. C. Maximum likelihood tree showing relationship of Aca-LPP-1 to other LPP-1 proteins. The percentage of trees in which the associated taxa clustered together is shown next to the branches. The A. thaliana sequence was designated as the out group. Ace, EYC42428.1; Cel, NP_001022378; At AAM63082; Mm, AAH61161; Hs, EAW54922; Dm, NP_649394.

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