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Table 2 Responsiveness of major antigenic spots of E. granulosus HF

From: Alteration of immunoproteome profile of Echinococcus granulosus hydatid fluid with progression of cystic echinococcosis

Spot no. (Description a ) No. of positive (% sensitivity) No. of negative (% specificity)
CE1 ( n= 11) CE2 ( n= 12) CE3 ( n= 12) CE4 ( n= 13) CE5 ( n= 11) Overall ( n= 59) AE ( n= 10) NC ( n= 10) Others b ( n= 30) Overall ( n= 50)
9 (Cathepsin B) 5 (45.5) 9 (75 ) 12 (100) 4 (30.8) 6 (85.7) 36 (61) 3 (30) 9 (90) 30 (100) 42 (84)
23 (38 kDa EgAg5) 4 (36.4) 11 (91.7) 12 (100) 7 (53.9) 9 (81.8) 43 (72.9) 2 (20) 6 (60) 30 (100) 38 (76)
24 (38 kDa EgAg5) 5 (45.5) 10 (83.3) 12 (100) 8 (61.5) 8 (72.7) 43 (72.9) 2 (20) 6 (60) 30 (100) 38 (76)
25 (38 kDa EgAg5) 6 (54.5) 10 (83.3) 12 (100) 8 (61.5) 8 (72.7) 44 (74.6) 2 (20) 6 (60) 30 (100) 38 (76)
26 (38 kDa EgAg5) 8 (72.7) 10 (83.3) 12 (100) 7 (53.8) 9 (81.8) 46 (80.0) 3 (30) 6 (60) 30 (100) 39 (78)
44 (EgAgB1/1) 0 (0) 10 (83.3) 10 (83.3) 7 (53.8) 0 (0) 27 (45.8) 8 (80) 10 (100) 30 (100) 48 (96)
45 (EgAgB1/1) 0 (0) 9 (75) 10 (83.3) 6 (46.2) 0 (0) 25 (42.4) 7 (70) 10 (100) 30 (100) 47 (94)
46 (EgAgB1/1) 0 (0) 10 (83.3) 11 (91.7) 5 (38.5) 0 (0) 26 (44.1) 8 (80) 10 (100) 30 (100) 48 (96)
47 (EgAgB1/1) 4 (36.4) 10 (83.3) 10 (83.3) 6 (46.2) 0 (0) 30 (50.8) 8 (80) 10 (100) 30 (100) 48 (96)
48 (EgAgB1/1) 3 (27.3) 9 (75) 10 (83.3) 5 (38.5) 0 (0) 27 (45.8) 7 (70) 10 (100) 30 (100) 47 (94)
61 (EgAgB1/1) 1 (9.1) 4 (33.3) 9 (75) 5 (38.5) 3 (27.3) 22 (37.3) 6 (60) 10 (100) 30 (100) 46 (92)
63 (EgAgB1/1) 4 (36.4) 9 (75) 12 (100) 7 (53.9) 6 (54.5) 38 (64.4) 7 (70) 10 (100) 30 (100) 47 (94)
66 (EgAgB1/1) 6 (54.5) 10 (83.3) 12 (100) 11 (84.6) 5 (45.5) 44 (74.6) 5 (50) 8 (80) 28 (93.3) 41 (82)
67 (EgAgB1/1) 5 (45.5) 9 (75) 12 (100) 5 (38.5) 2 (18.2) 33 (55.9) 7 (70) 10 (100) 30 (100) 47 (94)
69 (EgAgB1/1) 5 (45.5) 9 (75) 12 (100) 7 (53.8) 0 (0) 33 (55.9) 6 (60) 10 (100) 30 (100) 46 (92)
72 (EgAgB1 subunit) 6 (54.5) 10 (83.3) 12 (100) 10 (76.9) 7 (63.6) 45 (76.3) 7 (70) 10 (100) 30 (100) 47 (94)
73 (EgAgB1/1) 5 (45.6) 11 (91.7) 12 (100) 4 (30.8) 0 (0) 32 (54.2) 5 (50) 8 (80) 29 (96.7) 42 (84)
74 (EgAgB1/1) 4 (36.4) 10 (83.3) 12 (100) 5 (38.5) 4 (36.4) 32 (54.2) 7 (70) 10 (100) 30 (100) 47 (94)
75 (EgAgB2) 4 (36.4) 10 (83.3) 12 (100) 5 (38.5) 4 (36.4) 35 (59.3) 5 (50) 7 (70) 30 (100) 42 (84)
77 (EgAgB1/1) 4 (36.4) 12 (100) 12 (100) 5 (38.5) 6 (54.5) 39 (66.1) 6 (60) 10 (100) 30 (100) 46 (92)
  1. aProtein names were adapted from the GenBank database.
  2. bOthers included sparganosis, primary hepatocellular carcinoma, and normal controls (each of n = 10).