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Table 2 Responsiveness of major antigenic spots of E. granulosus HF

From: Alteration of immunoproteome profile of Echinococcus granulosus hydatid fluid with progression of cystic echinococcosis

Spot no. (Description a )

No. of positive (% sensitivity)

No. of negative (% specificity)

CE1 ( n  = 11)

CE2 ( n  = 12)

CE3 ( n  = 12)

CE4 ( n  = 13)

CE5 ( n  = 11)

Overall ( n  = 59)

AE ( n  = 10)

NC ( n  = 10)

Others b ( n  = 30)

Overall ( n  = 50)

9 (Cathepsin B)

5 (45.5)

9 (75 )

12 (100)

4 (30.8)

6 (85.7)

36 (61)

3 (30)

9 (90)

30 (100)

42 (84)

23 (38 kDa EgAg5)

4 (36.4)

11 (91.7)

12 (100)

7 (53.9)

9 (81.8)

43 (72.9)

2 (20)

6 (60)

30 (100)

38 (76)

24 (38 kDa EgAg5)

5 (45.5)

10 (83.3)

12 (100)

8 (61.5)

8 (72.7)

43 (72.9)

2 (20)

6 (60)

30 (100)

38 (76)

25 (38 kDa EgAg5)

6 (54.5)

10 (83.3)

12 (100)

8 (61.5)

8 (72.7)

44 (74.6)

2 (20)

6 (60)

30 (100)

38 (76)

26 (38 kDa EgAg5)

8 (72.7)

10 (83.3)

12 (100)

7 (53.8)

9 (81.8)

46 (80.0)

3 (30)

6 (60)

30 (100)

39 (78)

44 (EgAgB1/1)

0 (0)

10 (83.3)

10 (83.3)

7 (53.8)

0 (0)

27 (45.8)

8 (80)

10 (100)

30 (100)

48 (96)

45 (EgAgB1/1)

0 (0)

9 (75)

10 (83.3)

6 (46.2)

0 (0)

25 (42.4)

7 (70)

10 (100)

30 (100)

47 (94)

46 (EgAgB1/1)

0 (0)

10 (83.3)

11 (91.7)

5 (38.5)

0 (0)

26 (44.1)

8 (80)

10 (100)

30 (100)

48 (96)

47 (EgAgB1/1)

4 (36.4)

10 (83.3)

10 (83.3)

6 (46.2)

0 (0)

30 (50.8)

8 (80)

10 (100)

30 (100)

48 (96)

48 (EgAgB1/1)

3 (27.3)

9 (75)

10 (83.3)

5 (38.5)

0 (0)

27 (45.8)

7 (70)

10 (100)

30 (100)

47 (94)

61 (EgAgB1/1)

1 (9.1)

4 (33.3)

9 (75)

5 (38.5)

3 (27.3)

22 (37.3)

6 (60)

10 (100)

30 (100)

46 (92)

63 (EgAgB1/1)

4 (36.4)

9 (75)

12 (100)

7 (53.9)

6 (54.5)

38 (64.4)

7 (70)

10 (100)

30 (100)

47 (94)

66 (EgAgB1/1)

6 (54.5)

10 (83.3)

12 (100)

11 (84.6)

5 (45.5)

44 (74.6)

5 (50)

8 (80)

28 (93.3)

41 (82)

67 (EgAgB1/1)

5 (45.5)

9 (75)

12 (100)

5 (38.5)

2 (18.2)

33 (55.9)

7 (70)

10 (100)

30 (100)

47 (94)

69 (EgAgB1/1)

5 (45.5)

9 (75)

12 (100)

7 (53.8)

0 (0)

33 (55.9)

6 (60)

10 (100)

30 (100)

46 (92)

72 (EgAgB1 subunit)

6 (54.5)

10 (83.3)

12 (100)

10 (76.9)

7 (63.6)

45 (76.3)

7 (70)

10 (100)

30 (100)

47 (94)

73 (EgAgB1/1)

5 (45.6)

11 (91.7)

12 (100)

4 (30.8)

0 (0)

32 (54.2)

5 (50)

8 (80)

29 (96.7)

42 (84)

74 (EgAgB1/1)

4 (36.4)

10 (83.3)

12 (100)

5 (38.5)

4 (36.4)

32 (54.2)

7 (70)

10 (100)

30 (100)

47 (94)

75 (EgAgB2)

4 (36.4)

10 (83.3)

12 (100)

5 (38.5)

4 (36.4)

35 (59.3)

5 (50)

7 (70)

30 (100)

42 (84)

77 (EgAgB1/1)

4 (36.4)

12 (100)

12 (100)

5 (38.5)

6 (54.5)

39 (66.1)

6 (60)

10 (100)

30 (100)

46 (92)

  1. aProtein names were adapted from the GenBank database.
  2. bOthers included sparganosis, primary hepatocellular carcinoma, and normal controls (each of n = 10).
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