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Table 1 Clinical and biological signs suggesting canine monocytic ehrlichiosis used for dogs selection

From: Diagnosis and incidence risk of clinical canine monocytic ehrlichiosis under field conditions in Southern Europe

Clinical signs CBC 1 abnormalities Biochemistry abnormalities
Fever Moderate to severe thrombocytopenia Hypoalbuminemia
Depression, lethargy, weakness Anaemia Hyperglobulinemia
Anorexia Leukopenia Increase in
Lymphadenomegaly Lymphocytosis - alanine aminotransferase (ALT)
Splenomegaly   - alkaline phosphatase (ALP)
Haemorrhagic tendencies (including dermal petechiae and ecchymoses, epistaxis)   - C-reactive protein (CRP)
- alpha 1-acid glycoprotein (AAG)
Pale mucous membranes   
Weight loss   
Ophthalmological lesions (including anterior uveitis, chorioretinitis, papilledema, retinal haemorrhage, retinal perivascular infiltrates, bullous retinal detachment)   
Neurological disorders   
  1. 1Complete blood count.