Figure 4From: Hemozoin activates the innate immune system and reduces Plasmodium berghei infection in Anopheles gambiae Effect of hemozoin in vivo before and after the blood meal. Female A. gambiae were treated with 200 μg/ml sHz and fed with P. berghei-infected or naïve blood 24 h later. The expression of (A) REL2-F, REL1, Caspar, Cactus and (B) six immune related genes transcription was measured in the fat body before and after blood ingestion. Relative induction fold change was determined by qRT-PCR comparison to PBS-treated controls. Values represent the mean and SD of three independent experiments. Differences and P values: *(p < 0.05), **(p < 0.01), using the Student t test.Back to article page