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Table 1 Infection rates and number of CD11b + , CD11c + , or CD3 + cells infected with N. caninum -expressing GFP

From: Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections

  

Infection rates (%)

Infected cell number (×10 4 )

CD11b+ cells

WT

2.03 ± 0.70, P = 0.255

9.68 ± 3.05, P = 0.73

 

CCR5−/−

3.08 ± 1.93

9.09 ± 2.65

CD11c+ cells

WT

3.81 ± 1.01, P = 0.534

3.79 ± 1.27, P = 0.19

 

CCR5−/−

4.23 ± 1.23

2.85 ± 1.07

CD3+ cells

WT

0.30 ± 0.18, P = 0.131

0.55 ± 0.22, P = 0.45

 

CCR5−/−

0.80 ± 0.66

0.67 ± 0.31

  1. Peritoneal cells were obtained from CCR5−/− and C57BL/6 mice (WT) at 5 days after infection with 1 × 106  N. caninum tachyzoites expressing GFP (N = 6). Cells were then subjected to flow cytometry to determine the infection rate and absolute number of monocytes/macrophages (CD11b+), dendritic cells (CD11c+) and T cells (CD3+) based on GFP+ cells. Data were analyzed by a student’s t-test. GFP: green fluorescent protein.
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Parasites & Vectors

ISSN: 1756-3305

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