Figure 2

Worm and egg burdens are similar in AQP4 KO and WT mice infected with Schistosoma japonicum . At 3, 5, and 8 weeks after S. japonicum infection, four AQP4 WT or KO mice were randomly chosen and sacrificed and then perfused to calculate adult worms (A) or worm pairs (B). (C) The number of eggs extracted from the liver was determined by microscopic examination. Values are given as mean ± SD of 8 mice from two independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001.