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Figure 7 | Parasites & Vectors

Figure 7

From: An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum

Figure 7

CD4 + T cells from AQP4 KO mice display higher Th2 but lower Treg cells induction upon SEA stimulation in vitro . 8 weeks older AQP4 WT or KO mice were sacrificed, and single cell suspensions of splenocytes were prepared and in vitro stimulated with SEA as described in Materials and Methods for FCM. Cells were gated on the CD3+ population for analysis of proportions of Th2 (A), Th17 (B), and Th1 (C) cells in CD3+ T cells or on CD3+CD4+ population for analysis of proportion of Treg cells (D) in CD3+CD4+ T cells. FCM analyses were from one representative experiment. Results are expressed as mean ± SD of 24 mice from 3 independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001.

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