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Figure 1 | Parasites & Vectors

Figure 1

From: The expression dynamics of transforming growth factor-β/Smad signaling in the liver fibrosis experimentally caused by Clonorchis sinensis

Figure 1

Evaluation of hepatic fibrosis in mice caused by Clonorchis sinensis at 4 week post-infection (wk p.i.), 8 wk p.i. and 16 wk p.i. (A) Histological examination of liver tissues from C. sinensis-infected mice and normal control mice at different time-points as indicated. (B) Collagen depositions were specifically stained by Masson’s trichrome at different time-points as indicated. (C) Hydroxyproline (Hyp) concentration was measured in liver homogenate (0.1 g) in fibrotic or normal livers of BALB/c mice at indicated time-points. (D) Collagen depositions from each specimen were semi-quantified using Image-Pro Plus software. Data were presented as mean ± SEM from 8 C. sinensis-infected mice and 5 normal control (NC) mice at each time-point, * = P < 0.05, ** = P < 0.01, *** = P < 0.001 versus control mice.

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