Figure 4
The protein expression of Smad3 in livers and dynamic changes of serous TGF-β 1 in sera from C. sinensis -infected and non-infected mice . Mice were orally infected with 45 metacercariae of C. sinensis, livers and sera were collected from infected and non-infected mice at indicated time-points and the protein expression levels of Smad3 (A&B) in the livers and TGF-β1 (C) in the sera from mice were determined by western-blot and ELISA, respectively. Data were presented as mean ± SEM from 8 C. sinensis-infected mice and 5 normal control mice at each time-point, * = P < 0.05, ** = P < 0.01, *** = P < 0.001 versus control mice.