Figure 3From: Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver Change in transcription of genes involved in hepatotoxicity (blue bars), fibrosis (orange) and extracellular matrix formation (ECM) (red). Legend: Names on vertical axis represent proteins encoded by these genes. Coloured bars indicate the fold change between TPM values for infected compared with control sheep. Fold-change on the horizontal axis was calculated using averaged TPM values for infected and control groups. TGLN: transgelin, SLC2A3: solute carrier family 2 member 3, TIMP1: tissue inhibitor of metalloproteinases 1, TGF-β1: transforming growth factor beta 1, TNF: tumour necrosis factor, COL1A1: collagen, type I, alpha 1, OST: osteopontin and COL16A1: collagen, type I, alpha 1: collagen, type XVI, alpha 1.Back to article page