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Figure 3 | Parasites & Vectors

Figure 3

From: Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver

Figure 3

Change in transcription of genes involved in hepatotoxicity (blue bars), fibrosis (orange) and extracellular matrix formation (ECM) (red). Legend: Names on vertical axis represent proteins encoded by these genes. Coloured bars indicate the fold change between TPM values for infected compared with control sheep. Fold-change on the horizontal axis was calculated using averaged TPM values for infected and control groups. TGLN: transgelin, SLC2A3: solute carrier family 2 member 3, TIMP1: tissue inhibitor of metalloproteinases 1, TGF-β1: transforming growth factor beta 1, TNF: tumour necrosis factor, COL1A1: collagen, type I, alpha 1, OST: osteopontin and COL16A1: collagen, type I, alpha 1: collagen, type XVI, alpha 1.

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