Table 1 Geometric mean reductions in Demodex spp. mite counts of dogs treated once orally with Bravecto ™ or topically on three occasions at 28-day intervals with Advocate®
Study days | Study groups | Bravecto ™ | Advocate® | p-value |
|---|---|---|---|---|
−4 | Meana mite counts (n) | 447.0 | 509.4/478.6b | Nac |
Count range (n) | 41-1740 | 79-2724 | ||
28 | Meana mite counts (n) | 0.8 | 10.0 | |
Count range (n) | 0-14 | 0-496 | ||
Efficacy (%) | 99.8 | 98.0 | 0.0917 | |
56 | Meana mite counts (n) | 0.0 | 18.5 | |
Count range (n) | Nac | 0-115 | ||
Efficacy (%) | 100.0 | 96.4 | <0.0001 | |
84 | Meana mite counts (n) | 0.0 | 25.6 | |
Count range (n) | Nac | 0-286 | ||
Efficacy (%) | 100.0 | 94.7 | 0.0020 |