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Table 1 Experimental design for in vivo studies

From: Apoptosis mediated leishmanicidal activity of Azadirachta indica bioactive fractions is accompanied by Th1 immunostimulatory potential and therapeutic cure in vivo

Group 1 (Normal) Normal control/ Naïve mice (Administered PBS only)
Group 2 (INF) Infected control (BALB/c mice infected with L. donovani promastigotes and administered PBS)
Group 3 (VC) Vehicle control (0.5% DMSO in PBS, the highest concentration used to dissolve the fractions/compounds)
Group 4 (AmB) Amphotericin B administered intravenously (i.v.) at (5 mg/kg bw)
Group 5 (ALE100) ALE administered intraperitoneally (i.p.) at 100 mg/kg bw
Group 6 (ALE 200) ALE administered i.p. at 200 mg/kg bw
Group 7 (ASE100) ASE administered i.p. at 100 mg/kg bw
Group 8 (ASE200) ASE administered i.p. at 200 mg/kg bw