Study phase | Group number | Group treatment | Group function in respective phase |
---|---|---|---|
Post-vaccinal | 1 | Vaccinated once with vaccine strain | Evaluation of response to vaccination |
 | 2 | Inoculated with uninfected DH-82 cells | Control for group 1 |
Post-challenge | 1 | Vaccinated twice with vaccine strain and challenged with virulent E. canis strain | Evaluation of protection by vaccine and response to challenge |
 | 2 | Vaccinated once with vaccine strain and challenged with virulent E. canis strain | Evaluation of protection by vaccine and response to challenge |
 | 3 | Inoculated with uninfected DH-82 cells and challenged with virulent E. canis strain | Control for groups 1 and 2 |