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Figure 3 | Parasites & Vectors

Figure 3

From: Can the activation of plasminogen/plasmin system of the host by metabolic products of Dirofilaria immitis participate in heartworm disease endarteritis?

Figure 3

Type I Collagen degradation assay measured in culture supernatants from canine endothelial (A) and smooth muscle cells (B) untreated or treated with 1 μg/ml of DiES + 10 μg/ml of PLG, 1 μg/ml of DiES, 10 μg/ml of PLG, or with 1 μg/ml of DiES + 10 μg/ml of PLG + 50 mM of the εACA. The results were expressed as percentage of the Type I Collagen concentration in the culture supernatant from negative control cells (100%). Each point is the mean ± SD from three independent experiments. The asterisk (*) designates significant (p < 0.05) differences between DiES + PLG treatment and control groups.

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