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Figure 4 | Parasites & Vectors

Figure 4

From: Can the activation of plasminogen/plasmin system of the host by metabolic products of Dirofilaria immitis participate in heartworm disease endarteritis?

Figure 4

Representative zymography of culture supernatants from canine endothelial (A) and smooth muscle cells (B) untreated or treated with 1 μg/ml of DiES + 10 μg/ml of PLG, 1 μg/ml of DiES, 10 μg/ml of PLG, or with 1 μg/ml of DiES + 10 μg/ml of PLG + 50 mM of the εACA. Note the gelatinolytic bands associated with MMP-2 (72 KDa) and MMP-9 (92 KDa) levels. The results are expressed as percentage of the MMPs levels in the culture supernatant from negative control cells (100%). Each point is the mean ± SD from three independent experiments. The asterisk (*) designates significant (p < 0.05) differences between DiES + PLG treatment and control groups.

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Parasites & Vectors

ISSN: 1756-3305

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