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Figure 5 | Parasites & Vectors

Figure 5

From: Can the activation of plasminogen/plasmin system of the host by metabolic products of Dirofilaria immitis participate in heartworm disease endarteritis?

Figure 5

Effect of DiES on the expression of tPA (A), uPA (B), annexin A2 (C) and PAI-1 (D) in canine vascular endothelial (EC) and smooth muscle cells (SMC). Protein extracts from lysed DiES untreated or treated confluent cell cultures were analyzed by Western blot for tPA, uPA, annexin A2 and PAI-1. α-tubulin served as a protein control. Results were expressed as the mean ± SD of at least 3 independent experiments. The asterisk (*) designates significant (p < 0.05) differences from control cells. (Gray bars) Non-treated control cells. (Orange bars) Stimulated endothelial or smooth muscle cells with 1 μg/ml of DiES.

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Parasites & Vectors

ISSN: 1756-3305

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