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Figure 2 | Parasites & Vectors

Figure 2

From: Phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences

Figure 2

Congruent phylogenies of trypanosome species inferred using sequences from PRAC (A) and gGAPDH (B) genes. Maximum likelihood phylogenetic trees were inferred using entire TryPRAC nucleotide sequences from 13 trypanosome species (−Ln = 8403.576084), and gGAPDH sequences from 32 trypanosome species, non-trypanosome trypanosomatids of seven genera, and bodonids and euglenids as outgroups (−Ln = 13563.555163). Numbers on branches represent bootstrap support (>50) estimated with 100 pseudoreplicates in RAxML using GTRGAMMA. The arrow on the PRAC genealogy (A) indicates pseudogenes found in T. rangeli. The arrows on the gGAPDH tree (B) indicate the places hypothesised for the horizontal transference of bacterial PRAC gene to a common ancestor of Trypanosoma, and the gene loss in a common ancestor of T. brucei ssp. and T. congolense. Genbank accession numbers of PRAC and gGAPDH gene sequences are respectively showed in Table 1 and Additional file 1.

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Parasites & Vectors

ISSN: 1756-3305

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