Anti-glycan monoclonal antibodies provide protective immunity towards Schistosoma japonicum infection in mice. A. Immunofluorescence localization of antigens recognized by mAbs on cercaria and young worm of Schistosoma japonicum. Normal mouse IgG was used as negative control. B. Combined results from 3 separate animal experiments were shown on worm and egg burdens in infected mice treated with mAbs of 161.68 (n = 35), 517.77 (n = 33), 524.30 (n = 29) and mouse IgG (n = 33). EPG stands for the number of eggs per gram of liver tissue. One-way ANOVA was used to analyze the significance with *** as p < 0.001.