|
Hematopoietic cell lineage
|
CD59↓
|
-
|
FCER2↑
|
IL6R↑
|
IL1R2↑, CD59↑
|
-
|
|
Complement and coagulation cascades
|
CD59↓, C5AR1↓
|
-
|
-
|
C5AR1↑, C1R↑, CD59↑
|
C5AR1↑, CD59↑
|
-
|
|
Toll-like receptor signaling pathway
|
IRF7↓, MAP3K7IP2↓, MAPK9↓
|
IRAK1↑
|
-
|
IRAK1↑, MAP3K7IP2↑, MAPK9↑, IRF7↑
|
PIK3R2↑, MAPK9↑, IRF7↑
|
-
|
|
NOD-like receptor signaling pathway
|
SUGT1↓, MAP3K7IP2↓, MAPK9↓
|
-
|
-
|
MAP3K7IP2↑, MAPK9↑, SUGT1↑
|
MAPK9↑, SUGT1↑
|
-
|
|
RIG-I-like receptor signaling pathway
|
IRF7↓, LOC782671↓, MAPK9↓
|
-
|
-
|
LOC782671↑, MAPK9↑, IRF7↑
|
LOC782671↑, MAPK9↑, IRF7↑
|
-
|
|
Cytosolic DNA-sensing pathway
|
IRF7↓, LOC782671↓
|
-
|
-
|
LOC782671↑, IRF7↑
|
LOC782671↑, IRF7↑
|
-
|
|
Natural killer cell mediated cytotoxicity
|
FCER1G↓, PPP3R1↓
|
SHC1↑
|
-
|
PPP3R1↑, SHC1↑, FCER1G↑
|
PIK3R2↑, NFATC1↑, PPP3R1↑, FCER1G↑
|
SHC1↓
|
|
T cell receptor signaling pathway
|
PPP3R1↓, NCK2↑, PAK4↑
|
PAK4↑
|
-
|
NCK2↓, PPP3R1↑
|
PAK4↓, NCK2↓, PIK3R2↑, NFATC1↑, PPP3R1↑
|
-
|
|
B cell receptor signaling pathway
|
PPP3R1↓
|
-
|
-
|
PPP3R1↑
|
PIK3R2↑, NFATC1↑, PPP3R1↑
|
-
|
|
Fc epsilon RI signaling pathway
|
FCER1G↓, MAPK9↓
|
-
|
-
|
FCER1G↑, MAPK9↑
|
PIK3R2↑, MAPK9↑, FCER1G↑
|
-
|
|
Leukocyte transendothelial migration
|
CYBA↓, CYBB↑, MSN↓, CTNNB1↓, MYL9↑
|
-
|
-
|
CXCR4↓, MYL9↓, RHOH↓, CYBB↑
|
MYL9↓, RHOH↓, PIK3R2↑, CYBB↓, CYBA↑
|
-
|
|
Intestinal immune network for IgA production
|
TGFB1↓, PIGR↑, TGFB2↑
|
-
|
-
|
CXCR4↓, TGFB2↓, TGFB1↑
|
TGFB2↓, TGFB1↑
|
-
|
|
Cemokine signaling pathway
|
FOXO3↓, GNB2↓, GSK3A↓
|
SHC1↑, GSK3A↑
|
GSK3A↑
|
CXCR4↓, GNB2↑, FOXO3↑, GSK3A↑, SHC1↑
|
GNG10↓, PIK3R2↑, GSK3A↑, FOXO3↑, GNB2↑
|
SHC1↓
|
|
Fc gamma R-mediated phagocytosis
|
-
|
-
|
-
|
-
|
PIK3R2↑
|
-
|
