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Table 3 Clinical sensitivity and prevalence for UCP-LF assays and KK analysis

From: Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes

Kisumu set: N = 113 True positives a False negatives b Sensitivity Prevalence
Gold Standard 48 0 100% 42%
UCAA10 21 27 44% 19%
UCAA250 30 18 63% 27%
UCAA2000 47c 1 98% 42%
KK1-2 17 31 35% 15%
KK3-4 13 35 27% 12%
KK5-6 11 37 23% 10%
KK1-6 25 23 52% 22%
  1. aThe Gold Standard positive is defined as a sample (stool or paired urine) with at least a single egg in the 6-fold KK stool analysis or a CAA level > 0.3 pg/mL in urine as determined with the UCAA2000 assay.
  2. bFalse negatives are defined against the Gold Standard and calculated by ‘False Negatives = 48 – True Positives’.
  3. cNumber of UCAA2000 positives (including 16 additional positives, Figure 4).