Skip to main content

Table 3 Clinical sensitivity and prevalence for UCP-LF assays and KK analysis

From: Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes

Kisumu set: N = 113

True positives a

False negatives b

Sensitivity

Prevalence

Gold Standard

48

0

100%

42%

UCAA10

21

27

44%

19%

UCAA250

30

18

63%

27%

UCAA2000

47c

1

98%

42%

KK1-2

17

31

35%

15%

KK3-4

13

35

27%

12%

KK5-6

11

37

23%

10%

KK1-6

25

23

52%

22%

  1. aThe Gold Standard positive is defined as a sample (stool or paired urine) with at least a single egg in the 6-fold KK stool analysis or a CAA level > 0.3 pg/mL in urine as determined with the UCAA2000 assay.
  2. bFalse negatives are defined against the Gold Standard and calculated by ‘False Negatives = 48 – True Positives’.
  3. cNumber of UCAA2000 positives (including 16 additional positives, Figure 4).